Personal competition among colleagues and co-workers has been observed in order to prove their professional superiority over others.Such behaviors have grave consequences on the overall team performance.The aim of this study was to investigate the role of personal competition on team performance incorporating the mediating role of the playing dumb
Attenuation of morphine tolerance and dependence by thymoquinone in mice
Objectives: Dependence and tolerance are major restricting factors in the clinical click here use of opioid analgesics.In the present study, the effects of thymoquinone, the major constituent of Nigella sativa seeds, on morphine dependence and tolerance were investigated in mice.Materials and Methods: Male adult NMRI mice were made tolerant and dep
Ultrasound in pediatric rheumatology: Highlighting the differences with adults
Musculoskeletal ultrasound (MSUS) is a powerful tool of major importance in rheumatology.MSUS is ideally suited for the evaluation of pediatric patients because it is a safe technique with a high patient acceptability, it does not require sedation, and it is excellent for exploring multiple joints.It is also the most operator-dependent imaging moda
Failure to Genotype: A Cautionary Note on an Elusive loxP Sequence.
Here we report on a technical difficulty we encountered while optimizing genotyping strategies to identify mice derived from Exoc3l2tm1a(KOMP)Wtsi embryonic stem cells obtained from the Knockout Mouse Project Repository.The Exoc3l2tm1a(KOMP)Wtsi construct encodes a "knockout-first" design with loxP sites that confer conditional potential (KO1st).We
Structural Elucidation of Rift Valley Fever Virus L Protein towards the Discovery of Its Potential Inhibitors
Rift valley fever virus (RVFV) is the causative agent of a viral zoonosis that causes a significant clinical burden in domestic and wild ruminants.Major outbreaks of the virus occur in livestock, and contaminated animal products or arthropod vectors can transmit the virus to humans.The viral RNA-dependent RNA polymerase (RdRp; L protein) of the veg